Faizon Love was born in Santiago de Cuba and was raised in San Diego, California and Newark, New Jersey. Love got his start as a stand-up comedian and made his acting debut in an Off-Broadway at the age of 19. His motion-picture debut, Bebe's Kids, had him providing the voice of comedian Robin Harris, who died before production began on the film; Love offered a close vocal impression of Harris. He then had a role in The Meteor Man, starring Robert Townsend. Townsend then cast Love in a co-starring role on his sitcom The Parent 'Hood.
He followed up this role with a breakout performance as the drug supplier Big Worm in the 1995 film Friday. Follow-up films have included 3 Strikes, Elf, Don't Be a Menace to South Central While Drinking Your Juice in the Hood, Money Talks, Wonderland, The Fighting Temptations, and Idlewild. In 2001, Love guest-starred in the Ludacris single "Freaky Thangs" from the album Word of Mouf. The same year, he made a cameo appearance as a bus driver, in the music video for Lil Jon & The East Side Boys' single "Put Yo Hood Up".
Love co-starred in Couples Retreat (2009), a comedy film chronicling four couples who partake in therapy sessions at a tropical island resort. In 2012, he played the role of Stringer Bell in the satirical trailer for The Wire: The Musical. In June of that year, Love started to appear in a series of commercials for the pre-paid wireless provider Boost Mobile, promoting its new 4G phones.
In 2011, Love starred in a theatrical production of Our Town by Thornton Wilder, alongside Washington Wizards players Gilbert Arenas and Etan Thomas.